Collége de France
During her research career, Dr. Fuchs has been particularly interested in genetic and molecular aspects of neuronal dysfunction in the context of neurodegeneration. She is a M.D/Ph.D. currently leading a sub-group working on the homeoprotein Engrailed in dopaminergic physiology and pathophysiology in the group of Pr. Alain Prochiantz at the Center for Interdisciplinary Research in Biology at the Collège de France in France. As a physician by initial training, she is particularly motivated to conduct fundamental research with high translational potential. Dr. Fuchs has used electrophysiology, cell and molecular biology and functional genetic and genomics approaches to tackle central questions relevant to neurodegenerative diseases like amyotrophic lateral sclerosis and Huntington’s disease studying the selective vulnerability of neuronal populations (during her M.D. thesis), the genetic basis for sporadic and familial PD and the functional relevance of genetic variants (during her Ph.D. thesis) and the impact of the homeoprotein Engrailed on neuronal physiology and survival and as a therapeutic protein for PD (as a postdoc and research associate).