SESSION 3: LRRK2 AND GBA1 CELLULAR FUNCTION AND DYSFUNCTION II

SESSION CHAIR: Darren Moore, Ph.D. – Van Andel Institute

11:00 a.m.
LRRK2 and endolysosomal pathway
Sabine Hilfiker, Ph.D. – Rutgers, the State University of New Jersey

11:30 a.m.
GBA, synuclein degradation and lysosomal hydrolase trafficking
Joe Mazzulli, Ph.D. – Northwestern University Feinberg School of Medicine

12:00 p.m.
LRRK2 inhibition prevents endolysosomal deficits in Parkinson’s disease
Emily Rocha, Ph.D. – University of Pittsburgh

12:30 p.m.
Abstract selected talk
An Phu Tran Nguyen, Ph.D. – Van Andel Institute
Common coding variants in LRRK2 associated with Parkinson’s disease risk modulate LRRK2-dependent Rab10 phosphorylation

12:45 p.m.
Discussion

Location: Virtual Date: October 7, 2021 Time: 11:00 am - 1:00 pm Sabine Hilfiker, Ph.D. Joe Mazzulli, Ph.D. Emily Rocha, Ph.D.