Assistant Professor, Department of Neurology and Pittsburgh Institute for Neurodegenerative Diseases
University of Pittsburgh
Dr. Rocha is interested in the intersection between lysosomes and aging and how it impacts the onset of age-related neurodegenerative diseases. Dr. Rocha’s post-doctoral studies focused on lysosomal biology and the role glucocerebrosidase plays in a-synuclein accumulation in the context of Parkinson’s disease. Current projects include characterizing the link between impaired endolysosomal pathway and aging, understanding the role of mitophagy in Parkinson’s disease, and using various approaches (including antisense oligonucleotide, small-molecules, and gene therapy) to assess the therapeutic potential of different targets in animal models of Parkinson’s disease.