Assistant Professor, Center for Neurodegenerative Science
Van Andel Research Institute
Dr. Viviane Labrie earned her B.Sc. (honors) in human biology and her Ph.D. in genetics and neuroscience from University of Toronto under the direction of Dr. John Roder. She then completed a postdoctoral fellowship in the laboratory of Dr. Arturas Petronis at the Krembil Family Epigenetics Laboratory at the Centre for Addiction and Mental Health (CAMH) in Toronto. In 2016, Dr. Labrie joined Van Andel Research Institute’s Center for Neurodegenerative Science in Michigan as an assistant professor.
Dr. Labrie was among the first to characterize the role of a novel neurotransmitter D-serine in the brain and its role in schizophrenia. She also created new methods for mapping epigenetic marks and has contributed to the field’s understanding of a particular epigenetic mark called 5-hydroxymethylcytosine and its impact on brain function. Her work investigating the contribution of the epigenome to aging showed that different epigenetic changes with aging can underlie how genetic factors influence phenotypic outcomes in adulthood. Currently, Dr. Labrie’s research focuses on the molecular origins of neurodegenerative diseases in order to improve methods for early diagnosis and disease treatment. Her lab is particularly specialized in epigenetic epidemiology to understand the mechanisms involved in Parkinson’s and Alzheimer’s disease. Her work in Parkinson’s disease largely focuses on the role of the gastrointestinal (GI) tract in the initiation and development of this disease.